# GeneTech Tools - 基因技术知识引擎

> Comprehensive gene technology knowledge base covering genes, diseases, therapies, and CRISPR applications

## API Endpoints (JSON)

- `GET /api/data.json` - Complete structured data
- `GET /api/entities.json` - All entities flat list
- `GET /api/openapi.json` - OpenAPI 3.1 specification

## Stats

- Total entities: 402
- genes: 122
- diseases: 180
- gene_therapies: 59
- crispr_applications: 41

## Categories

### genes

- GENE-mpkp8lda-e2pwnv
- GENE-mpkp8lda-4td3uu
- GENE-mpkp8lda-0kvohs
- GENE-mpkp8lda-davw6o
- GENE-mpkp8ldb-8dncxy
- GENE-mpkp8ldb-tt87n6
- GENE-mpkp8ldb-ztdjwq
- GENE-mpkpaslv-yx524q
- GENE-mpkpaslv-b1y3l9
- GENE-mpkpaslw-1jvfxq
- GENE-mpkpaslw-5kp8lw
- GENE-mpkpg9e3-o1wzt2
- GENE-mpkpg9e3-4c67cl
- GENE-mpkpg9e3-0yiddu
- GENE-mpkpg9e3-wcoz9i
- GENE-mpkpg9e3-9l89t7
- GENE-mpkpg9e3-447xmw
- GENE-mpkpg9e3-rpz7do
- GENE-mpkpg9e3-5i9ptd
- GENE-mpkpg9e4-d4g4wc
- GENE-mpkpg9e4-3qdbe5
- GENE-mpkpg9e4-xw22up
- GENE-mpkpg9e4-u5cq2x
- GENE-mpkpg9e4-bfxq5o
- GENE-mpkpg9e4-wzfsrc
- GENE-mpkpg9e4-80xxny
- GENE-mpkpg9e4-m738wd
- GENE-mpkpmyed-b7d5yv
- GENE-mpkpmyed-lpdq3i
- GENE-mpkpmyed-x4sseb
- ... and 92 more

### diseases

- Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID)
- Rheumatoid Arthritis
- Rheumatic Diseases
- Breast Cancer Triple Negative
- Breast Cancer Stage II
- Breast Cancer Stage III
- Breast Cancer Invasive
- Diabetic Macular Edema
- Diabetic Retinopathy
- Squamous Cell Cancer of Head and Neck
- Triple Negative Breast Cancer
- Epithelial Ovarian Cancer
- Malignant Melanoma
- Advanced Solid Tumors
- Ovarian Cancer
- Prostate Cancer
- Pompe Disease (Late-onset)
- Granuloma
- Granulomatous Disease, Chronic
- Leukocyte Disease
- Genetic Disease, X-Linked
- Genetic Disease, Inborn
- Carcinoma, Non-Small-Cell Lung
- Breast Cancer
- HER2-low Breast Cancer
- epilepsy
- SLC6A1-related neurodevelopmental disorder
- developmental and epileptic encephalopathy
- Danon disease
- hypertrophic cardiomyopathy
- ... and 150 more

### gene_therapies

- GT-mpkp8lda-hi3fa1
- GT-mpkpaslw-a25iqs
- GT-mpkpaslw-nwk9i9
- GT-mpkpg9e3-2tktn5
- GT-mpkpg9e4-6v3fr3
- GT-mpkpg9e4-q1u85k
- GT-mpkpmyee-loh176
- GT-mpkpmyef-bj5sic
- GT-mpkpmyef-rqvtbz
- GT-mpkpmyef-31akmn
- GT-mpkpvwp3-mokzta
- GT-mpkq4tzt-nsr9im
- GT-mpkq4tzt-4uyva5
- GT-mpkq8hyu-tjy5mx
- GT-mpkq8hyu-88hf1t
- GT-mpkqew9m-l94834
- GT-mpkqew9m-ci0r15
- GT-mpktp0f6-kd739y
- GT-mpktp0f6-a9fwfj
- GT-f98bgwp0l6
- GT-4hbmciufjq
- GT-qg1nsmhccw
- GT-1mcimbiuyi
- GT-tg1kkqwogf
- GT-kresladi-lad1
- GT-cps1-crispr-personalized
- GT-novaiscB-compact
- GT-intellia-ttr-phase3
- GT-casgevy-expanded
- GT-nf2k8g1a
- ... and 29 more

### crispr_applications

- CR-mpkpg9e3-6ad71j
- CR-mpkpg9e4-mmdrqv
- CR-mpkpmyef-os0rvq
- CR-mpkqew9m-9xqkdm
- CR-mpkqew9m-5s6sfl
- CR-mpkqew9m-kfmtle
- CR-isvfvntxfm
- CR-tgida5ygo1
- CR-pucvb2b02n
- CR-ei0cu60kl5
- CR-yolt101-base-edit
- CR-pm359-prime-edit
- CR-chop-prime-edit-ucd
- CR-nf2k8c1a
- CR-nf2k8c2b
- CR-gt53100
- CR-gt53101
- CR-gt53102
- CR-0601-base-editing-advances
- CR-0601-crispr-10-companies
- CR-0601-250-trials
- CR-0601-nature-breakthrough
- CR-0601-fda-rare-disease
- CR-0602-fda-ultra-rare-pathway
- CR-0602-personalized-crispr
- CR-0602-250-trials-update
- CR-0602-yale-immune-crispr
- CR-0603-destructive-crispr
- CR-0603-in-vivo-advances
- CR-0603-fda-plausible-mechanism
- ... and 11 more

## Related Knowledge Bases

- [TCMDB](https://tcm.genetech.tools) - Pharmacogenomics bridges gene therapy with TCM
- [LifeDB](https://life.genetech.tools) - Gene editing enables synthetic biology
- [BrainDB](https://brain.genetech.tools) - Gene therapy for neurological disorders